VERVE-101: a promising CRISPR-based gene editing therapy that reduces LDL-C and PCSK9 levels in HeFH patients

Takahiro Horie, Koh Ono

Comparative analysis of lipid Nanoparticle-Mediated delivery of CRISPR-Cas9 RNP versus mRNA/sgRNA for gene editing in vitro and in vivo

Johanna Walther, Deja Porenta, Danny Wilbie

The Insights of Radical Science in the CRISPR Gene-Editing Era: A History of Science for the People and the Cambridge Recombinant DNA Controversy

Alyssa Botelho

In vivo PCSK9 gene editing using an all-in-one self-cleavage AAV-CRISPR system

Qian Li, Jing Su, Yi Liu

Top row from the left: Knock in in Silkworm, see Daimon <i>et al</i>., 14–25. Knock out in Xenopus laevis, see Suzuki <i>et al</i>., 108–114. Knock out in zebrafish, see Kawahara <i>et al</i>., 26–33. Knock out in medaka, see Kinoshita <i>et al</i>., 98–107. Middle row: Schematic drawings of the principal mechanisms of Genome editing by Zinc‐finger nucleases method, TAL effector nucleases method and CRISPR/Cas method, see Mashimo, 46–52, and Mashiko <i>et al</i>., 122–129. Bottom row from the left: Knock out in sea urchin, see Hosoi <i>et al</i>., 92–97. Knock out in rat,see Mashimo, 46–52. Transgenic marmoset, see Kishi <i>et al</i>., 53–62. Gene editing mediated by CRISPR/Cas method, see Mashiko <i>et al</i>., 122–129.

Delivering CRISPR: a review of the challenges and approaches

Christopher A. Lino, Jason C. Harper, James P. Carney et al.

CRISPR-Cas9 in vivo gene editing for transthyretin amyloidosis

Julian D. Gillmore, Ed Gane, Jörg Täubel

CRISPR in Public Health: The Health Equity Implications and Role of Community in Gene-Editing Research and Applications

Andrew M. Subica

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

Randall J. Platt, Sidi Chen, Yang Zhou

CRISPR-Cpf1-mediated genome editing and gene regulation in human cells

Tianwen Li, Linwen Zhu, Bingxiu Xiao

An efficient sorghum protoplast assay for transient gene expression and gene editing by CRISPR/Cas9

Ruirui Meng, Chenchen Wang, Lihua Wang

Selection of the high efficient sgRNA for CRISPR-Cas9 to edit herbicide related genes, PDS, ALS, and EPSPS in tomato

So Hee Yang, Euyeon Kim, Hyosun Park